Case studies
We’re dedicated to realizing your vision through a passionately progressive approach designed just for you. By taking this approach to every project, our world-class team with deep scientific and technical expertise help to unlock the full potential of your product.
Explore our full range of case studies below to discover how we’ve helped innovators just like you.
Delivering high quality recombinant proteins through advanced mammalian expression
A customer approached Enzene to address complex bispecific antibody expression and purification challenges while ensuring high purity and reproducible yields. Discover how we helped advance their program.
Enhancing productivity for animal health mAbs: from fed-batch to perfusion
A customer approached Enzene with an mAb clone for feline companion animals that had been developed at another CDMO. Low titers from the initial fed-batch process increased manufacturing costs and delayed development. Discover how Enzene optimized the process to accelerate the program.
Binder discovery using Enzene’s phage display platform
A customer approached Enzene seeking a discovery partner to generate a highly diverse antibody library and identify high-quality binders under tight development timelines. Discover how we helped accelerate their program.
Overcoming challenges for the production of a novel engineered mAb
Enzene Biosciences were opproached to help overcome an upstream batch bottleneck for their human-engineered mAb product.
Implementing enhanced lyophilized cycling for a stable drug product
A customer approached Enzene Biosciences for the development of a lyophilization cycle to produce a stable drug product that remained safe and efficacious. Find out how we helped them achieve therapeutic success.
Leveraging continuous manufacturing for efficient mAb production
Enzene Biosciences was approached by a customer working on a monoclonal antibody (mAb) for the treatment of osteoporosis in women who have an increased risk of fractures, but production suffered from low productivity. Find out how we helped them achieve therapeutic success.
Biosimilars: A comparability study
A customer approached Enzene Biosciences to complete comparability testing, focusing on the comparison of the physiochemical and biological properties of a biosimilar monoclonal antibody (mAb) drug product to the reference medicinal product (RMP). Find out how we helped them achieve success.
Optimizing manufacturing of a complex bispecific antibody
An emerging biotech approached Enzene Biosciences with a novel Fully Human Albumin Binding (FHAB) protein, which suffered from low titers, poor viability after 10 days of growth, proteolytic clipping, limited operational pH range, and host cell protein (HCP) problems. Find out how we helped them achieve success.
Harnessing a continuous perfusion process for improved productivity
A client approached Enzene, struggling to run a fed-batch beyond 10 days, which only produced a very low titer of 600 to 700 mg when cultured. Find out how we helped them achieve success.
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