Synthetic peptides
We leverage extensive expertise and advanced technologies to deliver high-quality synthetic peptides quickly and efficiently.
Why develop synthetic peptides?
Peptides offer several advantages as therapeutic molecules and have shown promise as treatments for complex disease indications. Their advantages include high specificity leading to reduced off-target effects, increased efficacy and low immunogenicity.
Understanding our synthetic peptide production
We offer a range of peptide synthesis services tailored to meet your requirements. Our peptide synthesis platform can help to navigate your peptide synthesis, with extensive experience in the development and manufacturing of peptide products from milligram to multigram scale. We can provide:
- In-depth scientific knowledge and understanding of solid, solution and hybrid phase peptide synthesis
- Process development and manufacturing for both solution and solid-phase peptide synthesis
- The design of scalable peptide syntheses through solid and solution phase synthesis
- Development of long-chain peptides (up to 40 amino acids), modified peptides, cyclic peptides and disulfide-bridged peptides
- Expertise in post-translational modifications like PEGylation, biotinylation, acetylation and amidation
- Purification method development using preparative HPLC
- Large-scale lyophilization of pure peptides
- Scale-up and tech transfer for gram-scale manufacturing
- GMP peptide manufacture to support clinical programs through the drug development pipeline
Our synthetic peptide facilities
Our state-of-the-art facilities are ready for your peptide synthesis project, including:
Equipment / Facility |
Specifications & Capacity |
|---|---|
| Automated Peptide Synthesizer | CS Bio, 200 L capacity |
| Manual Peptide Synthesis Reactor | 100 mL to 20 L capacity |
| Preparative HPLC | • Hanbon: 600 ml/min & 30 L/min flow rates • Waters: 300 L/min flow rate • YMC: 8.0 L/min flow rate |
| RP-HPLC Purification Columns | Sizes: 20 mm, 80 mm, 100 mm, and 450 mm |
| Lyophilizer | 6 kg and 100 kg condenser capacity |
| Storage Facility (Reagents) | 2–8°C (for amino acids & reagents) |
| Storage Facility (Product) | −20°C (for purified peptides) |
| Nanofiltration Unit | 5 L and 100 L capacity |
Why partner with Enzene for synthetic peptides?
We are a global CDMO and biosimilar developer dedicated to impacting the global healthcare landscape by bringing trusted and affordable medicines to market, quickly.
We understand that each modality has unique requirements, and we are committed to providing you with the highest quality products and services. Our flexible development and manufacturing platforms allow us to quickly and efficiently produce modalities, regardless of their complexity or scale.
Our proprietary continuous bioprocess manufacturing platform, EnzeneX® further enhances production, with accelerated rates and a significant reduction in the cost of producing complex modalities — from mAbs to complex proteins.
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A modality for every need
Fueled by our continuous innovation and armed with our wide variety of modalities, we are dedicated to bringing your biologics innovations to life.