Cell Line Engineering Company: Clone Development

Enzene’s Cell Line Engineering (CLE) department consists of a dedicated team of scientists and researchers working towards the development of high expressing production-grade microbial strains and mammalian cell lines for antibodies and difficult to express proteins. The in-house expression vector and host system are developed using the latest/cutting edge technologies from the field of molecular biology and cell line development.

Capabilities

Successfully developed high expressing microbial cell lines with products ready for commercialization.
Developed proprietary CHO cell lines for high expression of mAbs in Fed-Batch and Perfusion processes.
High throughput screening and automated Clone Selection with Process optimization in scalable miniature bioreactors.
Development of automated solutions for key stages within the cell line development workflow.

Infrastructure

CLE lab is equipped with world-class infrastructure and cutting edge equipment –

Fully automated clone selection systems like ClonePix 2 System.
BSL Class II Biosafety cabinets.
CO2 incubator shakers.
Latest qPCR and PCR systems.
Automated Cell imaging system.
Automated spectrophotometer for DNA, RNA, and protein quantification.
Bioinformatics software and tools