Synthetic Peptides - Enzene Biosciences Ltd

Offering high quality peptides at industry leading speed to help expedite your research
A new state-of-art peptide manufacturing facility at the existing plant site in Mandva, Gujrat adjacent to existing API facility is created to augment peptide production capacity. Peptide manufacturing unit is a cGMP DS manufacturing plant based in Mandva, Ankleshwar (Gujrat) having a built up capacity of 25,000 sq. ft. The facility is designed as per cGMP and complies with the latest USFDA guidelines. Advanced technology, latest equipment, enhanced safety and ease of operations and maintenance too is adopted in the new design.

The peptide synthesis team at Enzene has extensive experience in the development of peptide products from milligram to multigram scale. We have platforms for both solution and solid phase peptide synthesis. Our activities include designing scalable route of synthesis and purification technologies for peptides. Developing long chain peptides (upto 40 amino acids), modified peptides, cyclic peptides and disulphide bridged peptides. We also have expertise in post-translational modifications like PEGylation, biotinylation, acetylation, amidation. We have successfully transferred peptide synthesis process of uptomultigram scale for GMP manufacturing of therapeutic peptides.

Capabilities

Our in-depth scientific knowledge and understanding of solid, solution and hybrid phase of peptides synthesis makes us the ideal partner for peptide manufacturing
Developing a scalable route of synthesis of peptides through solid and solution phase synthesis
Manufacturing of peptides from milligram to multigram scale
Process development for the synthetic peptide with high quality
Method development for purification and purification of peptides through Preparative HPLC using the various types of column
Large scale lyophilization of pure peptide.
Scale up and tech transfer of process for gram scale manufacturing.
GMP peptide manufacture to support clinical programmes right through the drug development pipeline

Infrastructure

State of the art new peptide manufacturing facility
Fully automated peptide synthesizer (CS Bio) of 200 L capacity.
Manual peptide synthesis reactor 100 ml to 20 Lit.
Preparative HPLC (Hanbon flow 600 mL/min & 3.0 L/min, Waters flow 300 L/min and YMC flow 8.0 L/min).
RP-HPLC Purification columns of 20 mm, 50 mm, 80 mm, 100 mm 150 mm and 450 mm sizes
Lyophilizer (6 Kg and 100 Kg condenser capacity)
Storage facility at 2-8 oC for amino acids and reagents
Storage facility at -20 oC for purified peptide
Nanofiltration unit of (5 L and 100 L capacity)